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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Rank | Player | HR | YEAR | Open Postseason Leaderboard |
|---|---|---|---|---|
| 1 | Romualdo Rodríguez# | 10 | 1907-1911 | |
| 2 | Ernesto Gómez | 9 | 1902-1913 | |
| 3 | Eneas Núñez | 8 | 1907-1913 | |
| 3 | Álvaro Ramírez# | 8 | 1905-1911 | |
| 5 | Ashley Brace | 7 | 1901-1910 | |
| 5 | Hormisdas Reynoso | 7 | 1903-1913 | |
| 5 | Craig Rumpf | 7 | 1901-1910 | |
| 8 | Jesús Gallegos# | 6 | 1903-1913 | |
| 9 | Cristóbal Arceo# | 5 | 1903-1913 | |
| 9 | Enrique Facio | 5 | 1906-1914 | |
| 9 | Heráclito Guerrero# | 5 | 1903-1913 | |
| 9 | Luis Gómez# | 5 | 1906-1910 | |
| 9 | Clément Lamy | 5 | 1911-1914 | |
| 9 | Enrique Prado# | 5 | 1911-1914 | |
| 15 | Orlando Andrade | 4 | 1904-1913 | |
| 15 | Manuel Blas | 4 | 1903-1914 | |
| 15 | René González | 4 | 1902-1910 | |
| 15 | Benjamin Thurlow | 4 | 1901-1905 | |
| 15 | Rodulfo Velásquez# | 4 | 1906-1911 | |
| 20 | Virgilio Cantú | 3 | 1902-1910 | |
| 20 | Raúl Castillo# | 3 | 1904-1909 | |
| 20 | Keeran Dean | 3 | 1901-1911 | |
| 20 | Raúl Delgado# | 3 | 1903-1912 | |
| 20 | Trevor Glover | 3 | 1901-1902 | |
| 20 | Emanuel González | 3 | 1905-1913 | |
| 20 | Pitágoras Mateo | 3 | 1910-1914 | |
| 20 | Dennehy Miller | 3 | 1901-1908 | |
| 20 | Menandro Montenegro | 3 | 1903-1910 | |
| 20 | Eneas Morales | 3 | 1905-1914 | |
| 20 | Menandro Morales | 3 | 1910-1914 | |
| 20 | Baudelio Nava# | 3 | 1907-1911 | |
| 20 | Theo Scrivens | 3 | 1912-1913 | |
| 20 | Urayoán Soto | 3 | 1903-1914 | |
| 20 | Esteban Sánchez | 3 | 1902-1913 | |
| 20 | Aniceto Zacarías# | 3 | 1906-1908 | |
| 36 | José Aguilar | 2 | 1911-1914 | |
| 36 | Troilo Antuna# | 2 | 1903-1913 | |
| 36 | José Aranda# | 2 | 1906-1910 | |
| 36 | Jaime Barrientos | 2 | 1910-1914 | |
| 36 | Oisín Casey | 2 | 1901-1912 | |
| 36 | Agüeybaná Chávez# | 2 | 1907-1913 | |
| 36 | Gerard Clarke | 2 | 1901-1906 | |
| 36 | Mateo Cordova | 2 | 1902-1913 | |
| 36 | Joshua Craig | 2 | 1901-1909 | |
| 36 | José de León# | 2 | 1906-1914 | |
| 36 | Vicente Díaz# | 2 | 1910-1914 | |
| 36 | Ofelio Gaitán# | 2 | 1906-1911 | |
| 36 | Alfonso García# | 2 | 1905-1914 | |
| 36 | Apolodoro García# | 2 | 1905-1913 | |
| 36 | Rafael García | 2 | 1905-1914 | |
| 36 | Dave Ledlow | 2 | 1904-1913 | |
| 36 | Toby Lovatt | 2 | 1901-1913 | |
| 36 | Rubén Macías# | 2 | 1906-1911 | |
| 36 | Albán Marmolejo | 2 | 1910-1914 | |
| 36 | Adán Martínez | 2 | 1911-1914 | |
| 36 | Ernesto Martínez | 2 | 1904-1914 | |
| 36 | Ben Morrison | 2 | 1901-1914 | |
| 36 | Erón Méndez | 2 | 1910-1914 | |
| 36 | Cornelio Peláez | 2 | 1902-1913 | |
| 36 | Ryan Rae | 2 | 1901-1910 | |
| 36 | Ladislao Ruiz | 2 | 1902-1906 | |
| 36 | Robbie Scott | 2 | 1901-1904 | |
| 36 | Everton Smith | 2 | 1901-1912 | |
| 36 | Mo Taylor | 2 | 1901-1909 | |
| 36 | Julián Valdez | 2 | 1902-1913 | |
| 36 | Jerónimo Velasco# | 2 | 1911-1913 | |
| 36 | Jonás Vergara | 2 | 1905-1910 | |
| 68 | Joel Andrews | 1 | 1901-1905 | |
| 68 | Antenor Arguello# | 1 | 1911-1914 | |
| 68 | Abel Argueta# | 1 | 1909-1911 | |
| 68 | Cayetano Badía | 1 | 1905-1913 | |
| 68 | Mark Beattie | 1 | 1901-1907 | |
| 68 | Quentin Chapman | 1 | 1901-1905 | |
| 68 | Felipe Cortés | 1 | 1911-1913 | |
| 68 | Estanislao Díaz# | 1 | 1904-1911 | |
| 68 | Gabriel Elizondo | 1 | 1905-1910 | |
| 68 | José Elizondo | 1 | 1907-1913 | |
| 68 | Sorley Fitzpatrick | 1 | 1901-1905 | |
| 68 | Lisco Flores# | 1 | 1904-1911 | |
| 68 | Jeremy Freake | 1 | 1910-1914 | |
| 68 | Onesíforo Galan# | 1 | 1902-1910 | |
| 68 | Miguel Garlía# | 1 | 1903-1913 | |
| 68 | Samuel Gibson | 1 | 1901-1909 | |
| 68 | Daniel Gil | 1 | 1903-1913 | |
| 68 | Scott Graham | 1 | 1901-1904 | |
| 68 | Julián Guzmán | 1 | 1902-1914 | |
| 68 | Gaspar Gárnica | 1 | 1907-1914 | |
| 68 | Eugenio Hinojosa# | 1 | 1904-1914 | |
| 68 | Enrique Jiménez | 1 | 1907-1913 | |
| 68 | Shaun Love | 1 | 1901-1910 | |
| 68 | Eugenio López# | 1 | 1912-1913 | |
| 68 | Kellagh MacMahon | 1 | 1901-1902 | |
| 68 | Álvar Macías | 1 | 1906-1914 | |
| 68 | Bartolomé Magdaleno# | 1 | 1910-1914 | |
| 68 | Emilio Magdaleno# | 1 | 1902-1913 | |
| 68 | Luis Martínez# | 1 | 1904-1908 | |
| 68 | Martín Martínez# | 1 | 1902-1914 | |
| 68 | Luis Miranda# | 1 | 1911-1914 | |
| 68 | Tobías Molina# | 1 | 1903-1914 | |
| 68 | Cosme Morales | 1 | 1906-1911 |
