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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Rank | Player | W | YEAR | Open Season Leaderboard |
|---|---|---|---|---|
| 1 | Lisandro Acevedo# | 250 | 1902-1914 | |
| 2 | Fulco Quiñones# | 241 | 1901-1914 | |
| 3 | Teócrito Salinas | 223 | 1901-1913 | |
| 4 | Corey Lang | 207 | 1901-1913 | |
| 5 | Édgar Martínez# | 205 | 1903-1914 | |
| 5 | Ed Townsend | 205 | 1901-1913 | |
| 7 | Andrónico Lona | 202 | 1901-1914 | |
| 8 | Telémaco Aquino# | 199 | 1904-1914 | |
| 9 | Don Day | 194 | 1904-1914 | |
| 10 | Matt Kirby | 190 | 1904-1912 | |
| 11 | Lucas Galindo | 186 | 1901-1911 | |
| 12 | Tobías García | 179 | 1901-1910 | |
| 13 | Oliverio Rohena# | 178 | 1904-1914 | |
| 14 | Nicolás Lerma | 175 | 1901-1912 | |
| 15 | Darnell Wilson | 172 | 1904-1914 | |
| 15 | Lorenzo Álvarez | 172 | 1902-1911 | |
| 17 | Salvador Ramos# | 163 | 1904-1914 | |
| 18 | Jeremy Zinck | 155 | 1904-1914 | |
| 19 | Craig McGaughey | 154 | 1901-1912 | |
| 20 | Steve Noonan# | 151 | 1906-1914 | |
| 21 | Pedro Sánchez | 147 | 1904-1912 | |
| 22 | Anatolio Aguillón | 146 | 1901-1910 | |
| 22 | Celino Zambrano# | 146 | 1904-1913 | |
| 24 | Felipe Camarillo | 144 | 1901-1909 | |
| 25 | Federico Moya | 143 | 1905-1914 | |
| 26 | Tony Renny | 140 | 1904-1912 | |
| 27 | Gumersindo Rodríguez# | 139 | 1902-1913 | |
| 28 | Javier Villagómez | 138 | 1901-1910 | |
| 29 | Luis Aguilar# | 137 | 1906-1914 | |
| 30 | Roger Woodford | 134 | 1905-1914 | |
| 31 | Gabriel Gutiérrez | 133 | 1901-1913 | |
| 32 | Randy MacDermid | 131 | 1901-1912 | |
| 33 | Iapeto Martínez# | 129 | 1904-1911 | |
| 34 | Harland Vaillancourt | 128 | 1904-1911 | |
| 35 | Eduardo Ayala | 124 | 1904-1911 | |
| 35 | Bill Lannigan | 124 | 1904-1913 | |
| 37 | Alvin Stamp | 120 | 1904-1909 | |
| 38 | Tristán Guerrero | 114 | 1901-1909 | |
| 38 | Ezequiel Ramos | 114 | 1905-1912 | |
| 40 | Julián Villanueva | 113 | 1901-1908 | |
| 41 | Santiago Sánchez# | 112 | 1904-1914 | |
| 42 | Newton Ashe | 111 | 1901-1908 | |
| 43 | Alrigo Leitez# | 110 | 1907-1913 | |
| 43 | Leopoldo Reyes | 110 | 1904-1911 | |
| 45 | Brent Matchim | 109 | 1901-1909 | |
| 46 | Marcos González# | 108 | 1906-1914 | |
| 47 | Ernesto Lemus | 107 | 1906-1914 | |
| 48 | Luis Fernández# | 106 | 1907-1912 | |
| 49 | Terry Seaman | 105 | 1904-1913 | |
| 50 | Telémaco García | 104 | 1901-1910 | |
| 50 | Matías Jiménez | 104 | 1901-1909 | |
| 52 | Fermín Cruz# | 102 | 1906-1914 | |
| 52 | Víctor Gutiérrez# | 102 | 1906-1913 | |
| 54 | Marco Quesada | 101 | 1906-1912 | |
| 55 | Francisco Lerma | 100 | 1901-1911 | |
| 55 | Atenágoras Uribe | 100 | 1903-1914 | |
| 57 | Josh Holland | 99 | 1904-1911 | |
| 58 | Procopio Gómez | 97 | 1901-1911 | |
| 59 | Zósimo Santiago | 95 | 1904-1910 | |
| 60 | Jaime Bautista | 94 | 1906-1913 | |
| 60 | Armando Medina | 94 | 1901-1909 | |
| 62 | Enrique Hernández | 93 | 1905-1913 | |
| 62 | Paul Keys | 93 | 1901-1909 | |
| 62 | Adelio Mendiola | 93 | 1901-1909 | |
| 65 | Randolph McNutt | 91 | 1901-1907 | |
| 66 | Elías Jiménez | 90 | 1901-1905 | |
| 66 | Roberto Quevedo# | 90 | 1909-1914 | |
| 68 | Santiago Romero | 89 | 1902-1910 | |
| 69 | Dominic Simmons | 88 | 1901-1907 | |
| 70 | Trevor Lindsay | 87 | 1901-1905 | |
| 71 | Marco Martínez | 86 | 1906-1914 | |
| 71 | Jorge Rivera | 86 | 1905-1910 | |
| 73 | Agustín Aguirre# | 85 | 1908-1914 | |
| 73 | Enrique Ramos | 85 | 1901-1909 | |
| 75 | Rafael Godínez | 83 | 1901-1904 | |
| 75 | Pedro Ortiz | 83 | 1901-1907 | |
| 77 | Efraín Jurado# | 80 | 1905-1909 | |
| 77 | Pánfilo Zavala# | 80 | 1906-1911 | |
| 79 | Jesús Castellón# | 79 | 1910-1914 | |
| 79 | Rodrigo Fernández | 79 | 1901-1912 | |
| 79 | Ronaldo Martínez | 79 | 1901-1909 | |
| 82 | Greg McIlmoyle | 78 | 1901-1906 | |
| 83 | Ramiro Herrera | 77 | 1904-1910 | |
| 83 | Zacarías Manzanares | 77 | 1901-1905 | |
| 85 | Miguel Acevedo | 76 | 1904-1912 | |
| 85 | Príamo Díaz | 76 | 1910-1914 | |
| 85 | Apolonio Ruiz | 76 | 1901-1911 | |
| 88 | Ignacio Hernández | 75 | 1907-1913 | |
| 89 | Felipe González# | 74 | 1909-1914 | |
| 90 | Corey Bowman | 73 | 1901-1910 | |
| 90 | Jeffrey Hoffmann | 73 | 1901-1906 | |
| 90 | Álvaro Loredo | 73 | 1903-1913 | |
| 90 | Julián Loya# | 73 | 1906-1912 | |
| 90 | Jeremías Martín | 73 | 1901-1909 | |
| 90 | Normando Zapata | 73 | 1904-1911 | |
| 96 | Alberto Cortés | 72 | 1901-1911 | |
| 97 | Pablo Serrano | 69 | 1905-1910 | |
| 98 | Rodolfo Carbajal | 68 | 1901-1906 | |
| 98 | Dale Nealon | 68 | 1901-1909 | |
| 100 | Gabriel Martínez | 66 | 1906-1911 |
