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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Rank | Player | HR | YEAR | Open Season Leaderboard |
|---|---|---|---|---|
| 1 | Melquíades Ramos# | 106 | 1907-1914 | |
| 2 | Maurice Faye | 89 | 1901-1911 | |
| 3 | Herman Richards | 87 | 1901-1911 | |
| 4 | Higinio Navarro# | 86 | 1906-1914 | |
| 5 | Esteban Villareal | 83 | 1901-1910 | |
| 6 | Anaxímenes Vásquez# | 74 | 1903-1908 | |
| 7 | Tito Salcido# | 70 | 1903-1914 | |
| 8 | Luis Saldívar# | 66 | 1903-1913 | |
| 9 | Luis Almanza# | 50 | 1904-1914 | |
| 10 | Felipe Tolosa# | 49 | 1901-1914 | |
| 11 | Alberto Robles# | 45 | 1910-1914 | |
| 12 | Ademar González# | 41 | 1904-1914 | |
| 13 | Leopoldo de los Santos | 40 | 1901-1911 | |
| 14 | Enrique Franco# | 37 | 1906-1914 | |
| 15 | José Rizo | 32 | 1903-1911 | |
| 16 | Jerry Franklin | 30 | 1901-1912 | |
| 16 | Assane Mankou# | 30 | 1912-1914 | |
| 16 | Gavin Stokes | 30 | 1906-1912 | |
| 19 | Joe Peck | 28 | 1901-1906 | |
| 20 | Claudio Díaz | 27 | 1906-1914 | |
| 21 | Simon Dawson | 26 | 1908-1912 | |
| 21 | Pomare Lilia# | 26 | 1912-1914 | |
| 21 | Platón Robles | 26 | 1907-1913 | |
| 24 | Filóstrato Flores | 25 | 1901-1909 | |
| 25 | Luis Amaya# | 23 | 1912-1914 | |
| 25 | Fermín Ramírez | 23 | 1901-1909 | |
| 27 | François Girard | 22 | 1904-1911 | |
| 27 | Egidio Gurule | 22 | 1905-1912 | |
| 29 | Jesús Rodríguez | 20 | 1910-1912 | |
| 30 | Javier Hernández# | 19 | 1913-1914 | |
| 30 | Eugenio Torres | 19 | 1901-1907 | |
| 32 | Cory Peddle | 17 | 1901-1906 | |
| 33 | Pío Muñoz# | 15 | 1911-1914 | |
| 33 | Tibulo Ruiz | 15 | 1902-1911 | |
| 33 | Aldo Zamudio | 15 | 1901-1904 | |
| 36 | Barney Chiasson | 14 | 1912-1914 | |
| 36 | Jesús Flores | 14 | 1904-1912 | |
| 36 | Geoff Frazer | 14 | 1901-1909 | |
| 36 | Roque González | 14 | 1901-1905 | |
| 36 | Vicente Marín | 14 | 1906-1910 | |
| 36 | Eliseo Sostre | 14 | 1911-1913 | |
| 42 | Abelardo Coronel# | 13 | 1911-1914 | |
| 42 | Eugenio Martínez | 13 | 1901-1908 | |
| 42 | John Ruttan | 13 | 1901-1903 | |
| 45 | Zoilo Maldonado# | 12 | 1911-1914 | |
| 45 | Aluino Valerio | 12 | 1912-1912 | |
| 47 | Hormisdas Alonso# | 11 | 1913-1913 | |
| 47 | Prudencio Feliciano | 11 | 1901-1907 | |
| 47 | Lyndon Longchamps | 11 | 1911-1911 | |
| 47 | Leonel Neri | 11 | 1901-1905 | |
| 47 | Acón Ávila | 11 | 1901-1906 | |
| 52 | Alastair Bruce# | 10 | 1913-1914 | |
| 52 | Don Costello | 10 | 1901-1910 | |
| 52 | Pat Hannivan | 10 | 1901-1905 | |
| 52 | Ordoño Serrano# | 10 | 1910-1911 | |
| 56 | Vic Cope# | 9 | 1912-1914 | |
| 56 | Enrique Costello | 9 | 1903-1913 | |
| 58 | Jeff Harper | 8 | 1901-1911 | |
| 58 | Ricardo León | 8 | 1906-1909 | |
| 58 | Kyle Low | 8 | 1914-1914 | |
| 58 | Mitchell Macleod# | 8 | 1910-1913 | |
| 58 | Dane Mair# | 8 | 1914-1914 | |
| 58 | Calixto Mangual | 8 | 1910-1911 | |
| 58 | Eufrasio Ortega# | 8 | 1910-1912 | |
| 65 | Miguel Ángel Arredondo | 7 | 1906-1912 | |
| 65 | Fergal Clarke | 7 | 1910-1914 | |
| 65 | Leoncio Cruz | 7 | 1901-1909 | |
| 65 | Álvaro Flores# | 7 | 1913-1914 | |
| 65 | James Gardner# | 7 | 1910-1914 | |
| 65 | Stephen Hyde | 7 | 1913-1914 | |
| 65 | Telémaco Miramontes# | 7 | 1910-1913 | |
| 65 | Aníbal Morcillo# | 7 | 1910-1914 | |
| 65 | Dave Peterson | 7 | 1901-1910 | |
| 65 | Tofeeq Qasim# | 7 | 1912-1914 | |
| 65 | Semónides Rabadán | 7 | 1901-1907 | |
| 65 | Jacob Scott# | 7 | 1913-1914 | |
| 65 | Nicanor Sánchez# | 7 | 1913-1913 | |
| 65 | Callum Thomson# | 7 | 1911-1913 | |
| 65 | Casiodoro Vizcaíno | 7 | 1902-1905 | |
| 65 | Jayden Whitson# | 7 | 1911-1914 | |
| 81 | Catulo Campa | 6 | 1905-1912 | |
| 81 | Napoleón Candelario | 6 | 1901-1910 | |
| 81 | Emiliano Méndez | 6 | 1901-1910 | |
| 81 | Neftalí Ruiz# | 6 | 1910-1914 | |
| 81 | Sam Sheahan | 6 | 1913-1914 | |
| 86 | Roberto Azua# | 5 | 1911-1914 | |
| 86 | Laertes Cavazos# | 5 | 1911-1914 | |
| 86 | Koviljko Djorovic# | 5 | 1913-1914 | |
| 86 | Gabriel Gómez# | 5 | 1912-1914 | |
| 86 | Leo King | 5 | 1914-1914 | |
| 86 | Aca Ludmilov# | 5 | 1913-1914 | |
| 86 | Ramón Rodríguez# | 5 | 1911-1912 | |
| 86 | Leví Sánchez | 5 | 1903-1912 | |
| 86 | Édgar Torres | 5 | 1905-1909 | |
| 95 | Ezequiel Corujo | 4 | 1901-1907 | |
| 95 | Zabulón Guzmán | 4 | 1906-1912 | |
| 95 | Bradley Levick# | 4 | 1901-1914 | |
| 95 | Gualterio López# | 4 | 1912-1913 | |
| 95 | Ismael Peña | 4 | 1901-1909 | |
| 95 | Montel Re# | 4 | 1914-1914 |
