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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Rank | Player | HR | YEAR | Open Season Leaderboard |
|---|---|---|---|---|
| 1 | Timoteo Rodríguez# | 258 | 1902-1913 | |
| 2 | Jim Canavan | 253 | 1901-1908 | |
| 3 | Pablo González# | 214 | 1902-1912 | |
| 4 | Vicente García | 202 | 1902-1913 | |
| 5 | Santiago Vega | 201 | 1903-1911 | |
| 6 | Anatolio Méndez# | 191 | 1903-1911 | |
| 7 | Servio González# | 190 | 1906-1915 | |
| 8 | Igor Nieves# | 186 | 1902-1913 | |
| 9 | Medardo Cervantes# | 178 | 1908-1912 | |
| 10 | Modesto Ramírez# | 172 | 1902-1911 | |
| 11 | Plutarco Flores# | 165 | 1905-1911 | |
| 12 | An Thu | 158 | 1901-1912 | |
| 13 | Kyle Gardiner# | 156 | 1901-1914 | |
| 14 | Leoncio Savala# | 145 | 1906-1913 | |
| 15 | Juan Zamora | 143 | 1903-1912 | |
| 16 | Adrasto Tijerina# | 141 | 1903-1908 | |
| 17 | Hestio Castillo# | 140 | 1903-1912 | |
| 18 | Zenón Martínez# | 139 | 1903-1915 | |
| 18 | Luis Ramos# | 139 | 1903-1913 | |
| 20 | Jesús María Sánchez# | 137 | 1902-1914 | |
| 21 | Pascual Reyes | 133 | 1901-1911 | |
| 21 | Luis Santiago# | 133 | 1903-1914 | |
| 23 | Cletus Buffy | 131 | 1904-1912 | |
| 24 | Rodrigo González# | 129 | 1903-1913 | |
| 25 | Homero Gómez# | 127 | 1902-1915 | |
| 26 | Jorge Pesquera | 123 | 1905-1913 | |
| 27 | Simeón Martínez# | 122 | 1907-1915 | |
| 28 | Ademar Cisneros | 121 | 1907-1914 | |
| 29 | Timoteo de Armas# | 119 | 1905-1911 | |
| 29 | Lino Montes | 119 | 1903-1914 | |
| 31 | Guillermo Valdés | 117 | 1901-1913 | |
| 32 | Rosendo Mercado# | 115 | 1911-1915 | |
| 33 | Paulino Medina# | 114 | 1904-1915 | |
| 34 | Paul Spires | 112 | 1901-1910 | |
| 35 | Pelayo Peña | 111 | 1901-1911 | |
| 36 | Premislao Nolasco# | 110 | 1903-1915 | |
| 37 | José Salazar | 109 | 1902-1910 | |
| 38 | Armando Blancarte | 106 | 1903-1911 | |
| 38 | Gamaliel Fernández | 106 | 1901-1914 | |
| 38 | Héctor González# | 106 | 1908-1915 | |
| 38 | Héctor Nava | 106 | 1903-1912 | |
| 38 | Ángel Sotelo# | 106 | 1904-1915 | |
| 43 | Argimiro Liceaga# | 105 | 1903-1915 | |
| 44 | Valentín López | 104 | 1903-1912 | |
| 44 | Lorenzo Santillán | 104 | 1906-1913 | |
| 46 | Hilario Castillo | 103 | 1901-1914 | |
| 46 | Eneas Contreras# | 103 | 1908-1913 | |
| 46 | Dagoberto Villanueva# | 103 | 1903-1914 | |
| 49 | Bill Anderson | 102 | 1903-1912 | |
| 49 | Atanasio Parga | 102 | 1901-1911 | |
| 51 | Gaspar Campusano | 94 | 1901-1913 | |
| 51 | Aramis González | 94 | 1908-1914 | |
| 53 | Narciso Palacios | 93 | 1906-1914 | |
| 53 | Evaristo Velázquez | 93 | 1901-1912 | |
| 55 | Pascual Felipe# | 90 | 1904-1910 | |
| 56 | Eric Mallet | 89 | 1901-1913 | |
| 57 | Enrique Andrade | 88 | 1903-1915 | |
| 58 | Josías Godínez | 87 | 1901-1910 | |
| 58 | Arturo Ortiz | 87 | 1904-1911 | |
| 60 | Timón López | 86 | 1902-1912 | |
| 61 | Dave Carrere | 84 | 1911-1915 | |
| 61 | Hugh Hagy | 84 | 1901-1912 | |
| 61 | Rubén León# | 84 | 1911-1915 | |
| 64 | Catulo Bahena# | 83 | 1903-1915 | |
| 65 | Abenámar Andrade | 82 | 1903-1913 | |
| 65 | Jesús Castañeda | 82 | 1901-1914 | |
| 65 | José Ruiz | 82 | 1901-1914 | |
| 65 | Lorenzo Sena | 82 | 1901-1909 | |
| 69 | Mateo Zavala | 81 | 1902-1910 | |
| 70 | Quilvio Gómez | 80 | 1906-1914 | |
| 70 | Efraín Trejo | 80 | 1904-1914 | |
| 72 | Luis Cruz# | 79 | 1906-1915 | |
| 73 | Marcelo Antonio# | 78 | 1903-1913 | |
| 73 | Braulio Oyola | 78 | 1903-1913 | |
| 75 | Marco Antonio Quiñones | 77 | 1901-1912 | |
| 75 | Ildefonso Torres | 77 | 1901-1911 | |
| 77 | José Mateo# | 76 | 1904-1915 | |
| 78 | Eumeo Esquer | 75 | 1903-1914 | |
| 79 | Eufemio Viesca | 74 | 1903-1909 | |
| 80 | Telamón Palma | 73 | 1906-1909 | |
| 80 | Raúl Sánchez | 73 | 1904-1914 | |
| 80 | Jerónimo Torres# | 73 | 1903-1914 | |
| 83 | Ken Billman | 72 | 1901-1911 | |
| 84 | Jesús Cabrera | 70 | 1901-1909 | |
| 85 | Ryan Adams | 69 | 1901-1911 | |
| 85 | Lázaro García | 69 | 1902-1914 | |
| 85 | Admeto Hernández | 69 | 1905-1912 | |
| 85 | Elías Hinojos | 69 | 1903-1913 | |
| 85 | Ricardo Martín# | 69 | 1912-1915 | |
| 85 | Gabriel Sánchez | 69 | 1906-1913 | |
| 85 | Ousman Youssouf | 69 | 1904-1911 | |
| 92 | José Ruiz | 68 | 1904-1911 | |
| 93 | Jerónimo Guerra | 66 | 1901-1911 | |
| 94 | Teócrito Guillén | 64 | 1903-1913 | |
| 95 | Álvaro Molina | 63 | 1910-1913 | |
| 95 | Marco Mora# | 63 | 1905-1915 | |
| 95 | Pablo Rodríguez | 63 | 1902-1914 | |
| 95 | Daniel Shields | 63 | 1901-1909 | |
| 99 | Diego Contreras# | 62 | 1906-1913 | |
| 99 | Édgar Jaso | 62 | 1902-1910 |
