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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Rank | Player | HR | YEAR | Open Season Leaderboard |
|---|---|---|---|---|
| 1 | Loquillo Martínez | 328 | 1901-1914 | |
| 2 | Ulises Gómez | 309 | 1901-1911 | |
| 3 | Adam Miller | 303 | 1901-1914 | |
| 4 | Símaco Montes | 300 | 1901-1913 | |
| 5 | Octavio Álvarez | 294 | 1901-1913 | |
| 6 | Egidio Rodríguez | 293 | 1901-1914 | |
| 7 | Jorge Ruiz | 286 | 1901-1910 | |
| 8 | Julián Orúe | 275 | 1901-1911 | |
| 9 | Tito Padía | 241 | 1903-1914 | |
| 10 | Francisco Torras# | 231 | 1902-1915 | |
| 11 | Goliat Luján | 214 | 1901-1910 | |
| 12 | Marcos Castillo | 213 | 1901-1911 | |
| 12 | Nicandro González# | 213 | 1903-1914 | |
| 14 | Mike Skidmore | 207 | 1901-1911 | |
| 15 | Joseph Rolland | 205 | 1901-1911 | |
| 16 | Dalmacio Ramos | 201 | 1903-1915 | |
| 17 | Nicolás Almendares | 199 | 1901-1912 | |
| 18 | Oscar Carreno | 198 | 1901-1913 | |
| 18 | Íñigo León# | 198 | 1902-1915 | |
| 20 | Flavio Luis | 197 | 1901-1910 | |
| 20 | Florián Sandoval# | 197 | 1905-1914 | |
| 22 | Josh Dalton | 196 | 1901-1910 | |
| 23 | Alden Henn | 195 | 1902-1910 | |
| 23 | Oscar Soto | 195 | 1903-1913 | |
| 25 | Servio Chávez | 191 | 1901-1912 | |
| 26 | Virgilio Felán | 186 | 1901-1910 | |
| 27 | Lorenzo Cabrera | 182 | 1901-1911 | |
| 28 | Juan Padín | 181 | 1901-1910 | |
| 29 | Cristián Castillo | 178 | 1901-1909 | |
| 30 | Salomón Salazar | 175 | 1903-1913 | |
| 31 | Jaime González | 174 | 1901-1909 | |
| 32 | Michael Allan | 167 | 1904-1911 | |
| 33 | Epifanio Cuenca# | 166 | 1903-1915 | |
| 34 | Rafael Gutiérrez# | 164 | 1903-1915 | |
| 35 | Teófilo Espinal# | 160 | 1909-1915 | |
| 36 | Tony Shearer | 159 | 1901-1911 | |
| 36 | Flynn Stevens# | 159 | 1905-1915 | |
| 38 | Uranio Hinojosa | 157 | 1903-1911 | |
| 38 | Ulises Ramírez | 157 | 1901-1911 | |
| 40 | Bartolomé Carrada | 156 | 1903-1911 | |
| 40 | Felipe García | 156 | 1903-1913 | |
| 40 | Acacio Tejada | 156 | 1901-1911 | |
| 43 | Pablo Villada | 153 | 1902-1913 | |
| 44 | Efraín Castro | 151 | 1901-1911 | |
| 45 | Lázaro Carrillo# | 150 | 1903-1915 | |
| 45 | Diego Navarro# | 150 | 1905-1913 | |
| 45 | Rufo Porrata# | 150 | 1904-1915 | |
| 48 | Noé González | 149 | 1901-1911 | |
| 49 | Jesús Escobales | 148 | 1902-1912 | |
| 50 | Chris Dawson | 144 | 1901-1914 | |
| 50 | Marcus Gonzalez | 144 | 1910-1915 | |
| 50 | Matías Martínez# | 144 | 1905-1915 | |
| 53 | Patricio Rodríguez | 142 | 1901-1908 | |
| 54 | Mickey Roper | 141 | 1901-1909 | |
| 55 | Carlos Caballero | 136 | 1903-1912 | |
| 55 | Tito Rodríguez | 136 | 1904-1911 | |
| 57 | Evan O'Leary | 133 | 1906-1913 | |
| 58 | Anacleto Meléndez | 131 | 1906-1914 | |
| 59 | Francisco García# | 127 | 1905-1913 | |
| 60 | Julio Hernández | 125 | 1901-1912 | |
| 61 | Manuel Barragán | 124 | 1902-1912 | |
| 61 | Esteban Baubia# | 124 | 1906-1915 | |
| 61 | Próspero López# | 124 | 1910-1915 | |
| 64 | Héctor Cano | 122 | 1902-1914 | |
| 65 | Oliver Minasian | 120 | 1901-1910 | |
| 66 | Reginaldo Cervantes | 119 | 1901-1912 | |
| 67 | Ciriaco González | 117 | 1901-1909 | |
| 67 | Marcos Guevara | 117 | 1903-1912 | |
| 67 | Mateo Lugo | 117 | 1901-1907 | |
| 67 | Hugo Medrano# | 117 | 1906-1915 | |
| 67 | Matt Tulk | 117 | 1901-1908 | |
| 72 | Inocencio López# | 116 | 1903-1914 | |
| 73 | Francisco Aguilar# | 115 | 1910-1915 | |
| 74 | Álvaro Figueroa | 113 | 1903-1913 | |
| 75 | Adam Cotterill | 111 | 1907-1914 | |
| 76 | Osvaldo Rosales# | 109 | 1903-1913 | |
| 77 | Prudencio Ulloa# | 108 | 1906-1915 | |
| 78 | Semónides Cataño# | 107 | 1903-1909 | |
| 79 | José Cisneros# | 105 | 1902-1913 | |
| 80 | Firmino Carnossi | 104 | 1906-1914 | |
| 80 | Baltasar Medina | 104 | 1902-1911 | |
| 80 | Ramón Salinas | 104 | 1908-1914 | |
| 83 | Robert Troy | 103 | 1912-1914 | |
| 84 | Brandon Chalmers | 102 | 1901-1911 | |
| 85 | Cornelio Bazán# | 101 | 1904-1912 | |
| 86 | Darío Madrid# | 99 | 1910-1915 | |
| 86 | Ignacio Prado# | 99 | 1906-1912 | |
| 86 | Malik Sanford | 99 | 1910-1915 | |
| 89 | Vicente Valdez | 98 | 1901-1906 | |
| 90 | Emanuel Figueroa | 97 | 1901-1909 | |
| 90 | Juan Hernández# | 97 | 1908-1915 | |
| 90 | Stepán Sindelar# | 97 | 1910-1915 | |
| 93 | Rafael Montez | 96 | 1901-1908 | |
| 93 | Julio Morales | 96 | 1901-1909 | |
| 95 | Anthony Widdowson | 95 | 1909-1915 | |
| 96 | Jorge Campuzano | 94 | 1901-1906 | |
| 96 | Samuel Fernández | 94 | 1904-1912 | |
| 96 | Adrian Hahn | 94 | 1901-1913 | |
| 96 | Félix Ramírez | 94 | 1904-1911 | |
| 96 | Ginés Valdés | 94 | 1901-1909 |
