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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Rank | Player | HR | YEAR | Open Season Leaderboard |
|---|---|---|---|---|
| 1 | Jim Canavan | 227 | 1901-1908 | |
| 2 | Timoteo Rodríguez# | 195 | 1902-1913 | |
| 3 | Vicente García | 183 | 1902-1913 | |
| 4 | Medardo Cervantes# | 178 | 1908-1912 | |
| 5 | Santiago Vega | 175 | 1903-1911 | |
| 6 | Hestio Castillo# | 129 | 1903-1912 | |
| 7 | Cletus Buffy | 104 | 1904-1912 | |
| 8 | Guillermo Valdés | 103 | 1901-1913 | |
| 9 | Anatolio Méndez# | 101 | 1903-1911 | |
| 10 | Adrasto Tijerina# | 94 | 1903-1908 | |
| 11 | Eric Mallet | 89 | 1901-1913 | |
| 12 | Paulino Medina# | 88 | 1904-1915 | |
| 13 | Modesto Ramírez# | 75 | 1902-1911 | |
| 14 | José Ruiz | 68 | 1904-1911 | |
| 15 | Bill Anderson | 64 | 1903-1912 | |
| 16 | Rosendo Mercado# | 61 | 1911-1915 | |
| 17 | Pablo Rodríguez | 59 | 1902-1914 | |
| 18 | Héctor González# | 57 | 1908-1915 | |
| 19 | Valentín López | 55 | 1903-1912 | |
| 19 | Álvaro Molina | 55 | 1910-1913 | |
| 21 | Pascual Felipe# | 53 | 1904-1910 | |
| 22 | Hugh Hagy | 44 | 1901-1912 | |
| 23 | Eufemio Viesca | 40 | 1903-1909 | |
| 24 | Jesús Cabrera | 37 | 1901-1909 | |
| 24 | Esteban Villa# | 37 | 1910-1915 | |
| 26 | Pablo González# | 36 | 1902-1912 | |
| 26 | José Salazar | 36 | 1902-1910 | |
| 28 | Ken Billman | 35 | 1901-1911 | |
| 28 | Dave Carrere | 35 | 1911-1915 | |
| 30 | Pelayo Peña | 34 | 1901-1911 | |
| 30 | Bernardo Silva | 34 | 1912-1914 | |
| 32 | Claudio Silva# | 31 | 1906-1911 | |
| 33 | Rodrigo González# | 30 | 1903-1913 | |
| 33 | Marco Méndez# | 30 | 1906-1911 | |
| 33 | Javier Novo# | 30 | 1904-1912 | |
| 33 | Meliteo Rivera# | 30 | 1911-1914 | |
| 33 | Pat Wolfe | 30 | 1901-1911 | |
| 38 | Hilario Castillo | 28 | 1901-1914 | |
| 38 | Adrasto Garibay | 28 | 1901-1913 | |
| 38 | Vicente Vera | 28 | 1901-1908 | |
| 38 | Ousman Youssouf | 28 | 1904-1911 | |
| 42 | Tobías González# | 26 | 1906-1910 | |
| 43 | Leonel Ralda# | 25 | 1911-1915 | |
| 44 | Sebastián Álvarez | 23 | 1901-1909 | |
| 45 | Ruark Byrne# | 22 | 1906-1909 | |
| 45 | Luis López | 22 | 1903-1911 | |
| 47 | Shane Howey | 21 | 1913-1915 | |
| 47 | Ángel Niño# | 21 | 1906-1913 | |
| 47 | Jorge Rivera | 21 | 1912-1914 | |
| 50 | Juan Barajas | 20 | 1901-1909 | |
| 50 | Gerardo de los Santos | 20 | 1901-1907 | |
| 50 | José López# | 20 | 1912-1914 | |
| 50 | Austin Schall | 20 | 1901-1903 | |
| 54 | Argimiro Liceaga# | 19 | 1903-1915 | |
| 54 | Daniel Maldonado | 19 | 1901-1905 | |
| 54 | Raúl Reyes# | 19 | 1912-1915 | |
| 57 | Laureano López# | 18 | 1913-1915 | |
| 58 | Zenón Martínez# | 17 | 1903-1915 | |
| 58 | Jamie Moss | 17 | 1901-1904 | |
| 58 | Jerry Voeller | 17 | 1901-1914 | |
| 61 | Adán Calles | 16 | 1901-1906 | |
| 61 | Édgar Jaso | 16 | 1902-1910 | |
| 61 | Emanuel Leanos | 16 | 1910-1915 | |
| 61 | Anatolio Medina# | 16 | 1912-1915 | |
| 61 | Gabriel Nevárez# | 16 | 1903-1915 | |
| 61 | Rodrigo Polo | 16 | 1902-1911 | |
| 61 | Luis Santiago# | 16 | 1903-1914 | |
| 68 | Apolodoro Montoya | 15 | 1904-1911 | |
| 68 | Carlos Santos# | 15 | 1913-1914 | |
| 70 | Will Allison | 14 | 1912-1915 | |
| 70 | Roano Chávez | 14 | 1901-1911 | |
| 70 | Chris Cross | 14 | 1901-1911 | |
| 70 | Mililani Edewada# | 14 | 1913-1915 | |
| 70 | Douggie Knights | 14 | 1912-1913 | |
| 70 | Ambrosio López | 14 | 1901-1907 | |
| 70 | Cristóbal Méndez | 14 | 1901-1912 | |
| 70 | Édgar Nieto | 14 | 1903-1912 | |
| 70 | Paul Spires | 14 | 1901-1910 | |
| 70 | Rutilio Trejo# | 14 | 1910-1915 | |
| 70 | Alonso Verduzco# | 14 | 1915-1915 | |
| 81 | Petronio Anaya# | 13 | 1912-1915 | |
| 81 | Catulo Bahena# | 13 | 1903-1915 | |
| 81 | Taylor James | 13 | 1912-1915 | |
| 81 | Jesús Justiniano# | 13 | 1914-1915 | |
| 81 | Lalo López | 13 | 1901-1912 | |
| 81 | Callum Moffat | 13 | 1912-1914 | |
| 81 | Mario Torres# | 13 | 1910-1914 | |
| 88 | Pascual Cortés | 12 | 1901-1902 | |
| 88 | Jeremy Fratto | 12 | 1901-1906 | |
| 88 | Zacarías Fritsch# | 12 | 1914-1915 | |
| 88 | Urbano González# | 12 | 1904-1912 | |
| 88 | Pedro Hernández | 12 | 1901-1907 | |
| 88 | Zorba Kouretas | 12 | 1913-1915 | |
| 88 | Pascal le Guen | 12 | 1910-1914 | |
| 88 | Jorge Pesquera | 12 | 1905-1913 | |
| 88 | Mathis Picot# | 12 | 1914-1915 | |
| 88 | Rodolfo Ramírez# | 12 | 1912-1914 | |
| 88 | René Ruiz | 12 | 1902-1911 | |
| 88 | Lorenzo Sena | 12 | 1901-1909 | |
| 88 | Faro Serva | 12 | 1901-1909 |
