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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Rank | Player | HR | YEAR | Open Season Leaderboard |
|---|---|---|---|---|
| 1 | M. Izquierdo# | 191 | 1904-1915 | |
| 2 | Eugenio Murillo# | 183 | 1907-1915 | |
| 3 | Orran Lewis# | 175 | 1904-1915 | |
| 4 | Jesús García# | 158 | 1905-1915 | |
| 5 | Sófocles Díaz# | 119 | 1904-1915 | |
| 6 | Timoteo Contreras# | 118 | 1907-1915 | |
| 7 | Elijah Mann | 88 | 1904-1915 | |
| 8 | Chris Gridley# | 81 | 1905-1915 | |
| 9 | Ángel Pérez# | 80 | 1909-1915 | |
| 10 | Héctor Ríos# | 73 | 1905-1915 | |
| 11 | Uriel Álvarez# | 68 | 1906-1915 | |
| 12 | Richard Compton | 65 | 1907-1915 | |
| 13 | Micah James# | 53 | 1905-1915 | |
| 14 | Jaime Romano# | 49 | 1906-1915 | |
| 15 | Ossan Bruntoun# | 47 | 1906-1915 | |
| 15 | Alejandro Hernández# | 47 | 1906-1915 | |
| 17 | Gabriel Martínez# | 44 | 1905-1915 | |
| 18 | Hernando Medina# | 41 | 1911-1915 | |
| 19 | Vicente Esquivel# | 40 | 1904-1915 | |
| 19 | Dalmacio López# | 40 | 1904-1915 | |
| 21 | Scott Yarn | 39 | 1905-1914 | |
| 22 | Isidro Escudero# | 37 | 1906-1915 | |
| 22 | Diego Valenzuela# | 37 | 1906-1911 | |
| 24 | Toomey McLoughlin# | 36 | 1907-1915 | |
| 25 | Jesús Villalobos# | 33 | 1904-1915 | |
| 26 | Juan Rubio# | 31 | 1912-1915 | |
| 27 | Steve Collins# | 30 | 1905-1915 | |
| 27 | Frutos González# | 30 | 1906-1915 | |
| 29 | René Pedroza# | 29 | 1905-1915 | |
| 30 | Terry Meredith# | 25 | 1905-1912 | |
| 31 | Juan Moreno | 23 | 1904-1911 | |
| 31 | Rafael Osuna# | 23 | 1913-1915 | |
| 31 | Camilo Reyes# | 23 | 1907-1915 | |
| 34 | Carter Holgate | 22 | 1908-1914 | |
| 34 | Jerónimo Velasco# | 22 | 1914-1915 | |
| 36 | Dylan Howell | 21 | 1905-1914 | |
| 36 | Lane Komperda# | 21 | 1905-1915 | |
| 36 | Balbino Moreno# | 21 | 1909-1915 | |
| 39 | Fernando Castillo# | 20 | 1905-1915 | |
| 39 | Jack Stivetts | 20 | 1904-1914 | |
| 41 | Niso León# | 19 | 1906-1915 | |
| 42 | Gil Banks# | 18 | 1905-1915 | |
| 42 | Tristán Lemus# | 18 | 1906-1915 | |
| 44 | Taylor Cleaver | 16 | 1906-1915 | |
| 45 | Blake Carter# | 15 | 1905-1915 | |
| 45 | Roano Gómez# | 15 | 1904-1915 | |
| 45 | Pandolfo Vielma | 15 | 1904-1911 | |
| 48 | Jim Moriarty | 14 | 1905-1914 | |
| 48 | Darío Rodríguez# | 14 | 1914-1915 | |
| 48 | Sam Thompson | 14 | 1904-1906 | |
| 51 | Jason Bishop# | 13 | 1905-1915 | |
| 51 | Armando Castro# | 13 | 1905-1915 | |
| 51 | Mort Paoletti | 13 | 1904-1909 | |
| 51 | Ángel Vargas# | 13 | 1905-1915 | |
| 55 | Christopher Dyerson# | 12 | 1905-1915 | |
| 55 | Braulio Martín# | 12 | 1910-1915 | |
| 55 | Takeichi Nakano | 12 | 1915-1915 | |
| 55 | Vicente Perdomo | 12 | 1905-1915 | |
| 55 | Mark Smith# | 12 | 1905-1915 | |
| 55 | Harry Wolverton# | 12 | 1904-1915 | |
| 61 | Kid Elberfeld# | 11 | 1904-1915 | |
| 61 | Aaron Treadway | 11 | 1904-1911 | |
| 61 | Cleto Zambrano# | 11 | 1904-1915 | |
| 64 | Rafael Baldez# | 10 | 1904-1915 | |
| 64 | Greg Balthrop | 10 | 1904-1908 | |
| 64 | Jan Beal# | 10 | 1905-1915 | |
| 64 | Julião Guterres# | 10 | 1915-1915 | |
| 64 | Jeremy Lacy# | 10 | 1905-1915 | |
| 64 | Telmo Machado# | 10 | 1909-1915 | |
| 64 | Arturo Valenzuela# | 10 | 1906-1908 | |
| 71 | Rodrigo Aguilar | 9 | 1905-1915 | |
| 71 | Pete Browning | 9 | 1904-1906 | |
| 71 | Alarico Carreón# | 9 | 1906-1909 | |
| 71 | Julián Mendoza# | 9 | 1912-1915 | |
| 75 | Macario Soto# | 8 | 1911-1915 | |
| 75 | Leo Tenorio# | 8 | 1913-1915 | |
| 75 | Herminio Valadez | 8 | 1904-1912 | |
| 75 | Clodovindo Yzaguirre# | 8 | 1906-1915 | |
| 79 | Horacio Colón | 7 | 1904-1913 | |
| 79 | Reggie Howell# | 7 | 1904-1915 | |
| 79 | Harry Lumley | 7 | 1904-1905 | |
| 79 | Amadís López# | 7 | 1905-1915 | |
| 79 | Enrique Maldonado# | 7 | 1906-1915 | |
| 79 | Jaime Martínez# | 7 | 1915-1915 | |
| 79 | Hestio Ruiz# | 7 | 1909-1915 | |
| 79 | Francisco Santa Cruz# | 7 | 1904-1915 | |
| 79 | Tomás Velásquez# | 7 | 1909-1915 | |
| 79 | Bill Winchel# | 7 | 1905-1915 | |
| 89 | Ángel Cabrera# | 6 | 1912-1915 | |
| 89 | Ross Hirst# | 6 | 1905-1915 | |
| 89 | Valeriano Luján# | 6 | 1908-1915 | |
| 89 | Evaristo López | 6 | 1904-1911 | |
| 89 | Arvin McMartin | 6 | 1905-1914 | |
| 89 | Cristián Márquez# | 6 | 1905-1910 | |
| 89 | Andy Otto | 6 | 1906-1914 | |
| 89 | Natán Quezada# | 6 | 1906-1915 | |
| 89 | Ethan Smith# | 6 | 1905-1915 | |
| 89 | Brian Tate# | 6 | 1905-1915 | |
| 89 | Severo Ávila# | 6 | 1905-1915 | |
| 100 | Leo Cedillo | 5 | 1907-1914 |
