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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Rank | Player | ERA | YEAR | Open Postseason Leaderboard |
|---|---|---|---|---|
| 1 | Javier Beltrán# | 0.500 | 1904-1906 | |
| 2 | Abilio Rivera# | 0.587 | 1906-1915 | |
| 3 | Karim Anbar# | 0.726 | 1903-1912 | |
| 4 | Artemisio Cárdenas# | 0.900 | 1903-1915 | |
| 5 | Miguel García# | 1.005 | 1904-1915 | |
| 6 | Julio Rodríguez# | 1.047 | 1905-1915 | |
| 7 | Juan Fernández | 1.063 | 1903-1913 | |
| 8 | Quilvio Argueta | 1.100 | 1903-1907 | |
| 9 | Celedonio Gutiérrez# | 1.125 | 1905-1915 | |
| 10 | Everton Stack | 1.156 | 1903-1914 | |
| 11 | Marco Cepeda# | 1.157 | 1906-1915 | |
| 12 | Beltrán Ramírez | 1.167 | 1901-1904 | |
| 13 | Aureliano Santa# | 1.277 | 1905-1915 | |
| 14 | Cristián Partida# | 1.333 | 1905-1912 | |
| 15 | Pascual Magdaleno# | 1.415 | 1903-1915 | |
| 16 | Hermenegildo Solís# | 1.443 | 1905-1915 | |
| 17 | José Adame# | 1.467 | 1904-1915 | |
| 18 | Zacarías Nájera# | 1.473 | 1902-1906 | |
| 19 | Redmond Brier# | 1.565 | 1906-1915 | |
| 20 | Rubén García# | 1.577 | 1905-1915 | |
| 21 | Teodoro Morales# | 1.588 | 1903-1915 | |
| 22 | Alejo Núñez | 1.600 | 1901-1906 | |
| 23 | Julio García# | 1.631 | 1903-1915 | |
| 24 | Alberto Garfias# | 1.653 | 1902-1910 | |
| 25 | Graciano Colón | 1.670 | 1901-1903 | |
| 26 | Evan Brooks | 1.688 | 1911-1915 | |
| 27 | Jan Pajkos | 1.689 | 1902-1913 | |
| 28 | Carmelo Castillo# | 1.737 | 1903-1915 | |
| 29 | Romualdo García | 1.746 | 1901-1905 | |
| 30 | Luis Sánchez# | 1.748 | 1906-1915 | |
| 31 | Columbano Alvarado# | 1.783 | 1905-1915 | |
| 32 | Luis Castro# | 1.800 | 1903-1915 | |
| 32 | Matthew Johnstone | 1.800 | 1901-1904 | |
| 32 | Cándido Rivera# | 1.800 | 1906-1915 | |
| 32 | Jean Rivière# | 1.800 | 1905-1911 | |
| 36 | Plácido Polanco# | 1.808 | 1902-1915 | |
| 37 | Luis Gallardo | 1.822 | 1903-1906 | |
| 38 | Alejandro Cerda# | 1.826 | 1903-1915 | |
| 39 | Gabriel Morales# | 1.829 | 1912-1915 | |
| 40 | Simeón Elizondo | 1.841 | 1902-1905 | |
| 41 | Ezequiel Vásquez# | 1.855 | 1903-1915 | |
| 42 | Emanuel Reyes | 1.869 | 1902-1907 | |
| 43 | Mario Vásquez | 1.897 | 1901-1905 | |
| 44 | Isidoro García# | 1.900 | 1902-1915 | |
| 45 | Héctor Varela# | 1.901 | 1902-1908 | |
| 46 | Ronit Robinson# | 1.913 | 1906-1915 | |
| 47 | Guillermo Rivera# | 1.926 | 1904-1915 | |
| 48 | Gabriel Palacios# | 1.927 | 1910-1915 | |
| 49 | Manuel Cortés# | 1.937 | 1903-1915 | |
| 50 | Tomás Pérez# | 1.941 | 1904-1915 | |
| 51 | Leví Esparza# | 1.957 | 1905-1915 | |
| 52 | Leonel Téllez# | 1.964 | 1906-1915 | |
| 53 | Marco Acosta# | 1.967 | 1902-1915 | |
| 54 | Pedro Cárdenas | 1.971 | 1902-1910 | |
| 55 | Raúl Marín# | 1.992 | 1903-1915 | |
| 56 | Alcides Camacho# | 1.996 | 1904-1915 | |
| 57 | Fernando Mota# | 1.997 | 1902-1915 | |
| 58 | Eunosto Gutiérrez# | 2.006 | 1902-1915 | |
| 59 | Isma'il Farraj# | 2.011 | 1905-1914 | |
| 60 | Pablo Peres# | 2.019 | 1904-1914 | |
| 61 | Alistair Oakley | 2.038 | 1901-1904 | |
| 62 | Nicolás Arreguín# | 2.041 | 1905-1915 | |
| 63 | Jerónimo Beauchamp | 2.045 | 1901-1903 | |
| 63 | Ben Downie | 2.045 | 1902-1906 | |
| 63 | Absalón Rodríguez# | 2.045 | 1910-1915 | |
| 66 | Sarpedón Castillo | 2.057 | 1901-1902 | |
| 66 | Cristóbal Ponce | 2.057 | 1904-1905 | |
| 68 | Bill Ewing | 2.077 | 1901-1901 | |
| 68 | Rubén Piñón | 2.077 | 1901-1905 | |
| 70 | Rafael García# | 2.083 | 1903-1915 | |
| 71 | Anatolio Castellanos# | 2.087 | 1906-1915 | |
| 72 | Harland Wadden | 2.088 | 1904-1909 | |
| 73 | Tibulo Rodríguez# | 2.112 | 1905-1915 | |
| 73 | Diego Sánchez# | 2.112 | 1902-1915 | |
| 75 | Leonel Alvarrán# | 2.118 | 1903-1915 | |
| 75 | Germán Jiménez | 2.118 | 1901-1905 | |
| 75 | Juan Martín | 2.118 | 1901-1906 | |
| 78 | Aniceto La Chataigneraie# | 2.139 | 1908-1915 | |
| 79 | Miguel Vásquez# | 2.141 | 1904-1915 | |
| 80 | Nicolás Luna# | 2.150 | 1904-1915 | |
| 81 | René Calva# | 2.151 | 1904-1915 | |
| 82 | Miguel Escobar# | 2.156 | 1905-1909 | |
| 83 | Judá García# | 2.160 | 1905-1915 | |
| 84 | Renato Díaz# | 2.171 | 1903-1915 | |
| 85 | Jeffrey McCarthy | 2.172 | 1901-1903 | |
| 86 | Mike Lowry | 2.174 | 1903-1915 | |
| 87 | Ted Balloon# | 2.175 | 1901-1915 | |
| 88 | Nicodemo Caballero# | 2.181 | 1904-1915 | |
| 89 | Eugenio Hernández# | 2.192 | 1902-1915 | |
| 90 | Andrew Mullen | 2.219 | 1901-1909 | |
| 90 | Álvaro Salas# | 2.219 | 1909-1915 | |
| 92 | Clodovindo López# | 2.250 | 1906-1909 | |
| 93 | Armando Rodríguez# | 2.262 | 1902-1915 | |
| 94 | Gerardo Rodríguez# | 2.279 | 1903-1915 | |
| 95 | Pedro Silva# | 2.282 | 1904-1908 | |
| 96 | Yann Bourgeois# | 2.288 | 1904-1915 | |
| 97 | Luis Larios | 2.292 | 1902-1907 | |
| 97 | Padraic Quinlevan# | 2.292 | 1902-1908 | |
| 99 | Luis Barajas | 2.298 | 1901-1907 | |
| 100 | Beckan Tranent# | 2.302 | 1906-1915 |
